Touch screen is generally responsive. The only place I have hard time getting it to work is in the lock screen. Screen responds during the unlock period but the lag time is more than 2 seconds which shouldn’t be the case.
The power button : This might be a personal preference but I found the power button on Mi410 inconvenient. When you hold the phone, for you turn on the phone you need an extra hand. This operation should typically be handled with just one hand. At least that’s how I grew up with. A southpaw might find the placement perfect because I was able to hold and turn the phone on with my left hand. The design should be agnostic to your dexterity. I have also mentioned about how the power button can be accidently pressed on while taking a picture in my first impressions.